Immunolocalization of Estrogen Receptor Alpha in Adult Female Rat Hippocampus
نویسندگان
چکیده
منابع مشابه
Immunohistochemical colocalization of estrogen receptor-α and GABA in adult female rat hippocampus
BACKGROUND Hippocampus is an important target for estrogen action. It is severely affected in patients of Alzheimer's disease. Much of the current research related to estrogen and brain function is focused in two directions. PURPOSE By attempting to lacalize localizing ERs in GABAergic neurons of the hippocampus we tried to test the hypothesis that the action of estrogen in maintaining the ne...
متن کاملEstrogen and aging affect the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats.
Estrogen replacement increases both the number of dendritic spines and the density of axospinous synapses in the hippocampal CA1 region in young rats, yet this is attenuated in aged rats. The estrogen receptor-alpha (ER-alpha) is localized within select spines of CA1 pyramidal cells in young animals and thus may be involved locally in this process. The present study investigated the effects of ...
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The hippocampal system plays an important role in memory function. Neurohormones like androgens and estrogens that syntheses in hippocampus have an important role in learning and memory. Many biological effects of estrogens in the brain via estrogenic receptors (ERs) are investigated. The current research has conducted to assess the effect of estrogenic receptors on spatial discrimination in ra...
متن کاملThe Role of Estrogen Receptors on Spatial Learning and Memory in CA1 Region of Adult Male Rat Hippocampus
The hippocampal system plays an important role in memory function. Neurohormones like androgens and estrogens that syntheses in hippocampus have an important role in learning and memory. Many biological effects of estrogens in the brain via estrogenic receptors (ERs) are investigated. The current research has conducted to assess the effect of estrogenic receptors on spatial discrimination in ra...
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Objective Background: Failure in the endometrial receptivity may account for a significant number of infertility cases including unexplained infertility in women. Reduction in the endometrial estrogen receptor-alpha (ER-α) expression during window of implantation may be a critical event that coincides with expression of specific genes and providing a receptive endometrium. The aim of present st...
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ژورنال
عنوان ژورنال: International Journal of Morphology
سال: 2010
ISSN: 0717-9502
DOI: 10.4067/s0717-95022010000200024